Yes, many hosts offer delivery and setup services for campervans and RVs, often for an additional fee or within a specific distance from their location. This allows you to enjoy the RV experience without the hassle of driving or towing. You can filter the search results to show just listings offering delivery.
In most cases, a regular driver's license is sufficient to drive an RV rental. However, if the RV is large (e.g. over 45 feet long or you're towing something weighing more than 10,000 pounds), a special or commercial license may be required. Check the rules of the states you will be travelling through as they can vary.
One-way rentals are generally not widely available with private hosts, although some do offer that option. It's usually easier to arrange one-way rentals with commercial RV rental suppliers.
Some private offer unlimited miles on rentals, however not all. See listing details for specifics, or use the filter in search results.